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Boric Acid Clinical Evidence

Clinicians’ Use of Intravaginal Boric Acid Maintenance Therapy for Recurrent Vulvovaginal Candidiasis and Bacterial Vaginosis. Powell A, Ghanem KG, Rogers L, Zinalabedini A, Brotman RM, Zenilman J, Tuddenham S. (PubMed

Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence. Iavazzo C, Gkegkes ID, Zarkada IM, Falagas ME. (PubMed

Intravaginal boric acid: is it an alternative therapeutic option for vaginal trichomoniasis? Thorley N, Ross J. (PubMed

Vulvovaginal Candidiasis: A Review of the Evidence for the 2021 Centers for Disease Control and Prevention of Sexually Transmitted Infections Treatment Guidelines. Nyirjesy P, Brookhart C, Lazenby G, Schwebke J, Sobel JD. (PubMed)

Data on Safety of Intravaginal Boric Acid Use in Pregnant and Nonpregnant Women: A Narrative Review. Mittelstaedt R, Kretz A, Levine M, Handa VL, Ghanem KG, Sobel JD, Powell A, Tuddenham S. (PubMed


The antimicrobial effect of boric acid on Trichomonas vaginalis. Brittingham A, Wilson WA. (PubMed

Antifungal mechanisms supporting boric acid therapy of Candida vaginitis. De Seta F, Schmidt M, Vu B, Essmann M, Larsen B. (PubMed

BASIC study: is intravaginal boric acid non-inferior to metronidazole in symptomatic bacterial vaginosis? Study protocol for a randomized controlled trial. Zeron Mullins M, Trouton KM. (PubMed

Prevalence of Candida glabrata and its response to boric acid vaginal suppositories in comparison with oral fluconazole in patients with diabetes and vulvovaginal candidiasis. Ray D, Goswami R, Banerjee U, Dadhwal V, Goswami D, Mandal P, Sreenivas V, Kochupillai N. (PubMed

Prolonged (3-month) mycological cure rate after boric acid suppositories in diabetic women with vulvovaginal candidiasis. Ray D, Goswami R, Dadhwal V, Goswami D, Banerjee U, Kochupillai N. (PubMed

Treatment of vulvovaginal candidiasis with boric acid powder. Van Slyke KK, Michel VP, Rein MF. (PubMed

Boric acid addition to suppressive antimicrobial therapy for recurrent bacterial vaginosis. Reichman O, Akins R, Sobel JD. (PubMed

Treatment of Torulopsis glabrata vaginitis: retrospective review of boric acid therapy. Sobel JD, Chaim W. (PubMed

Treatment of vaginitis caused by Candida glabrata: use of topical boric acid and flucytosine. Sobel JD, Chaim W, Nagappan V, Leaman D. (PubMed

Recurrent Bacterial Vaginosis: An Unmet Therapeutic Challenge. Experience With a Combination Pharmacotherapy Long-Term Suppressive Regimen. Surapaneni S, Akins R, Sobel JD. (PubMed

Efficacy of maintenance therapy with topical boric acid in comparison with oral itraconazole in the treatment of recurrent vulvovaginal candidiasis. Guaschino S, De Seta F, Sartore A, Ricci G, De Santo D, Piccoli M, Alberico S. (PubMed

Common complementary and alternative therapies for yeast vaginitis and bacterial vaginosis: a systematic review. Van Kessel K, Assefi N, Marrazzo J, Eckert L (PubMed

Current therapy of vulvovaginitis. Rein MF. (PubMed

Candida lusitaniae as an unusual cause of recurrent vaginitis and its successful treatment with intravaginal boric acid. Silverman NS, Morgan M, Nichols WS. (PubMed

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